Premplantation Genetic Testing For Aneuploidies (PGT-A)
PGT-A is a tool used by experts at RADfertility to optimize the efficiency of IVF, increasing the likelihood of a healthy pregnancy.
What Is Preimplantation Genetic Testing For Aneuploidies (PGT-A)?
An embryo that appears healthy can contain chromosomal abnormalities. Preimplantation Genetic Testing for Aneuploidies provides information regarding the chromosomal health of the embryo. PGT-A can greatly enhance the chance of selecting the healthiest embryo, increasing the likelihood of a healthy pregnancy.
Patient Benefits of PGT-A
- High implantation and pregnancy rates (about 60%) and extremely low miscarriage rates (>10%)
- Enhanced confidence in single embryo transfer stemming from embryologist identifying chromosomally normal embryos that have the highest chance of implantation
- Safer IVF stimulation cycles that avoid hyper stimulation syndrome almost 100% of the time
- Enhanced fetal growth and pregnancy outcome with frozen embryo transfer
- The ability to identify and freeze healthy embryos for fertility preservation for future pregnancy wishes
- Provides credible information for patients considering donor egg or embryo adoption in situations where no embryos are chromosomally normal (typical in older patients)
IVF For ME Success Rates (Jan. 2010 – Dec. 2015)
|Age at Time of Retrieval||All Ages||<30||30-34||35-39||>39|
|Number of Thaws/Transfers||415||41||169||165||40|
|Percent Embryo Survival||99.1%||100%||98.9%||98.8%||100%|
|Ongoing Clinical Pregnancy Rate||59.2%||61%||61%||57.3%||57.5%|
|Mean Embryos Transferred||1||1||1.1||1||1.1|
- IVF with PGT-A (IVF For ME) – Ages <30 61% 61%
- IVF without PGT-A (Traditional IVF) – Ages <30 49.6% 49.6%
- IVF with PGT-A (IVF For ME) – Ages <30 61% 61%
- IVF without PGT-A (Traditional IVF) – Ages <30 47.4% 47.4%
- IVF with PGT-A (IVF For ME) – Ages <30 57.3% 57.3%
- IVF without PGT-A (Traditional IVF) – Ages <30 30.9% 30.9%
- IVF with PGT-A (IVF For ME) – Ages >39 57.5% 57.5%
- IVF without PGT-A (Traditional IVF) – Ages >39 17.4% 17.4%
National averages published by SART are found here. RAD-specific statistics published by SART can be found here.
***A comparison of clinic success rates may not be meaningful because patient medical characteristics, treatment approaches, and entrance criteria for ART may vary from clinic to clinic.
***Source: 2015 SART Report, Final Cumulative Outcome Per Egg Retrieval Cycle
When To Consider PGT-A
We offer PGT-A to all IVF patients. Those interested in this testing will be counseled to consider whether PGT-A makes sense for them. Common indications for recommending PGT-A include:
- Maternal age over 34
- Paternal age over 40
- Unexplained infertility at any age
- Prior failed IVF without explanations
- Prior pregnancy losses
- Diminished ovarian reserve (i.e. low AMH, high FSH)
- PGT-A is included in our IVF For ME™ Program
Articles & Publications
Gateway to IVF Success: The ABSs of PGT-A – October 1, 2014
IVF has actually become more efficient over recent years, with the development of newer and better lab culture conditions. Exciting research developments exploring genes and DNA have yielded a perfect collaboration between IVF centers and genetics experts. Dr. Feinberg touches on the importance of incorporating PGT-A into current IVF treatments.
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Preimplantation genetic testing for aneuploidies (PGT-A) is a tool used to optimize the efficiency of IVF, increasing the likelihood of a successful pregnancy.
PGT-M and PGT-SR
Preimplantation genetic testing for monogenic/single gene defects (PGT-M) and (PGT-SR) are tests that help evaluate embryos for genetic risk factors.
IVF Success Rates
We lead the way through research and innovation contributing to nationally recognized success.
Peggy Sue O.
"I feel so lucky to have found RADfertility. I tried two other clinics before I expanded my search and found RADfertility. I drive an hour each way to go to them but I don’t regret a thing. They are so caring and so professional. Every time I message them they respond quickly. Every time I see them they have a friendly smile and warm welcome. They explain everything so well and I never feel lost in the process as I did elsewhere. They also took the time to figure out what was wrong. Other clinics threw up their hands, said 'I don’t know' and pushed me to try IVF."
"Dr. Feinberg and the entire staff at RADfertility are absolutely amazing. The receptionists, coordinators, nurses, and lab staff are compassionate, caring, and straight forward. I’ve had a 12-year infertility journey and I’ve tried other clinics but RADfertility was the only one I felt at ease with. They answered any questions that I had and were there any time I needed them. My coordinator, Amy, was the absolute best and always had my back. Dr. Feinberg’s dedication to his patients is incredible. You are not just a number there, you are a person with individualized needs and care."
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"My journey with RADfertility and Dr. McGuirk started when my husband and I were trying to conceive and were having difficulty. We went to RADfertility, where we met Dr. McGuirk. I always say she changed my life and 'fixed' me. Dr. McGuirk is always learning more about endometriosis and how to help her patients. She’s brilliant and truly cares for you! I’m eternally grateful to her and everyone at RADfertility for their unwavering support, love, and care."
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"RADfertility's staff has heart and provided me with exceptional health care. I knew I was in good hands and felt like we were in this together. The doctors and nursing staff always answered all of my questions and provided thorough information about all of my options. I am so fortunate and appreciative of the care that I received at RADfertility. They go above and beyond."
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Anonymous on FertilityIQ
"Dr. Schillings always kept us informed and never gave up on us. She always explained our options and risks with each procedure. She called us personally when there were any issues or sensitive subjects to cover. Dr. Schillings was the first doctor that had answers for us and wanted to help us have our miracle baby!"
4735 Ogletown-Stanton Road
Medical Arts Pavilion 2
Newark, DE 19713
Silverside Medical Center
2700 Silverside Road, Suite 2A
Wilmington, DE 19810
Eden Hill Medical Center
200 Banning Street, Suite 240
Dover, DE 19904
Phone: (302) 602-8822
Fax: (302) 602-8832